Automated Gait Analysis for Rodents Based on the Catwalk Method.
This turnkey system evaluates the impact of locomotion defects that can arise due to a variety of reasons such as, for example, Parkinson’s disease, spinal cord injuries, arthritis, ataxia, and traumatic brain injuries. By taking into account more than 20 parameters, not only does the system reduce your time spent analyzing, but it also provides more advanced and precise results than what is achieved by manual scoring.
GaitLab bundle hardware and software
The camera starts recording as soon as the experiment starts, when the rodent is placed on the walkway. Each footprint is automatically analyzed and classified by the software, and you will be provided with a comprehensive graphical comparison between different groups of animals as soon as a significant amount of rodents has been through the system.
Spreadsheet results exist for both static and dynamic parameters.
Each one of your rodent’s paws is automatically categorized and illuminated. The different endpoints assessed are diverse: animal speed, footprint area, paw area, mean intensity, number of contact areas, etc. They can be chosen depending on your field of interest.
The GaitLab device was designed to motivate rodents in a non-intrusive manner to often cross from the runway to the shelter. The ‘goal box’ included provides rodents with food pellets, encouraging them to approch it. The type of motivation results in better outputs.
GaitLab allows you to be fully in control of every parameter before, during and after any experiment. Know everything about the conditions of the experiment beforehand thanks to the automated runway cleanliness status and trial validation. All the conditions can be controlled and repeated.
A sofware tailored to your needs
By choosing to associate the GaitLab hardware to its software, information will be extracted from a large range of parameters. Some of them are illustrated in the image below.
These capabilities will help your laboratory achieve outstanding results
Reliable imaging over time
High-resolution recording and analysis.
Immediate validation and continuous count of the valid trials (based on several criteria such as speed).
Be notified promptly if your latest trial is not suitable for scoring, allowing you to re-run the animal right away.
The lack of roof allows for easy access to the animal and cleaning.
Index of cleanliness
Rest assured that the walkways are rated by an index of cleanliness, allowing each footfall's pressure to be interpreted.
All you need in one document
Quantitative gait analysis system for rodents
Review worldwide scientific papers using our tracking systems
Imbalance of Neuregulin1-ErbB2/3 signaling underlies altered myelin homeostasis in models of Charcot-Marie-Tooth disease type 4H
Major motor and gait defcits with sexual dimorphism in a Shank3 mutant mouse model
Long noncoding RNA BS-DRL1 modulates the DNA damage response and genome stability by interacting with HMGB1 in neurons
Major motor and gait defcits with sexual dimorphism in a Shank3 mutant mouse mode
Sex-dependent behavioral de ficits and neuropathology in a maternal immune activation model of autism
Motor Impairments Correlate with Social Deficits and Restricted Neuronal Loss in an Environmental Model of Autism
Interested in this solution?
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